The Onset EZ™ Pen buffers individual cartridges of local anesthetic to a neutral pH — eliminating the sting, the wait, and the guesswork.
Standard local anesthetic is acidic — that's why it stings and why onset takes so long. Buffering raises the pH to physiologic levels right before injection.
Buffer a cartridge in under 3 seconds. No training. No assembly. Just press and go.
Patients report no stinging 'zing' — a virtually painless injection that calms needle anxiety.
Profound numbness almost immediately. See more patients without rushing a single one.




Load any standard local anesthetic cartridge directly into the Onset EZ Pen.
A precisely metered dose of sterile sodium bicarbonate adjusts the pH in under 3 seconds.
Profound anesthesia onset means you can start the procedure right away.
One pen, 30 doses
Designed for use on every injection — not just the difficult ones.
Practitioners across general dentistry, oral surgery, and academia on what changed after they started buffering.
Each Onset EZ Pen contains a sterile solution of 8.4% Sodium Bicarbonate — enough to buffer 30 local anesthetic cartridges. Fully disposable. No extra sharps waste.

A sterile solution of 8.4% Sodium Bicarbonate and Water for Injection — enough to buffer 30 cartridges of local anesthetic.
Yes. The Onset EZ Pen buffers standard local anesthetic cartridges you already use.
Under 3 seconds per cartridge. There's no assembly, no training, and no learning curve.
At roughly $3.50 per buffered injection, it's priced to use on every patient — not just the difficult cases.
Join the practices delivering profound, near-instant numbness on every injection.